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Moderna shares soared as much as 100% on Wednesday after the company and partner Merck announced that their personalized mRNA cancer vaccine met both primary goals in a pivotal late-stage melanoma trial — the first positive Phase 3 result ever…

Merck and Moderna announced Wednesday that their personalized mRNA cancer vaccine succeeded in a Phase 3 clinical trial, marking the first late-stage positive readout for an individualized neoantigen therapy and for any mRNA-based cancer treatment.

Sanofi has filed federal lawsuits against both Moderna and Pfizer, alleging their COVID-19 vaccines infringe the French drugmaker's patents covering mRNA technology, according to Reuters.

Moderna and the University of Oxford announced on June 8 that their Phase 1/2 trial of mRNA-4194, an investigational mRNA-based cancer vaccine targeting Lynch syndrome, has received authorization from the UK's Medicines and Healthcare products Regulatory Agency. The trial, called…