pediatrics

Novo Nordisk says Wegovy helped 2 in 5 young children beat obesity in trial

Novo Nordisk on Monday announced that its blockbuster weight-loss drug semaglutide, marketed as Wegovy, helped two in five young children move below the obesity threshold in a landmark clinical trial — the first to test the GLP-1 medication in children…

CRISPR therapy shows promise in children as young as 5 with sickle cell disease

HCA Healthcare announced on Monday that research published in The New England Journal of Medicine demonstrates promising results from a CRISPR gene-editing therapy tested in children ages 5 to 11 with severe sickle cell disease and transfusion-dependent beta thalassemia, marking…

OpenAI’s o3 model helped diagnose 18 children with unsolved rare diseases

Researchers at Boston Children's Hospital and Harvard used OpenAI's o3 Deep Research model to identify 18 new diagnoses among children whose rare genetic diseases had stumped clinicians for years, according to a study published Wednesday in NEJM AI.