CAR T cell therapy

CAR T-cell therapy drives severe arthritis into remission in first trial

Researchers at Charité—Universitätsmedizin Berlin have demonstrated for the first time that CAR T-cell therapy can drive severe rheumatoid arthritis into sustained remission, according to results from the COMPARE trial published in Nature Medicine on August 27, 2026. Disease activity decreased…

Penn researchers use AI to find new CAR T therapy targets

Researchers at Penn Medicine have developed an artificial intelligence framework that combines large language models with human scientific expertise to systematically discover new targets for CAR T cell therapy, publishing their findings Wednesday in the journal Cell.